COTRIM DS
Generic Name: sulfamethoxazole and trimethoprim (SUL fa meth OX a zole and trye METH oh prim)
Brand Names: COTRIM DS, MEGATRIM DS, BACTIPONT DS
What is Bactrim DS (sulfamethoxazole and trimethoprim)?
Sulfamethoxazole and trimethoprim are both antibiotics that treat different types of infection caused by bacteria.
The combination of sulfamethoxazole and trimethoprim is used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, and Pneumocystis carinii pneumonia.
Sulfamethoxazole and trimethoprim may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Bactrim DS (sulfamethoxazole and trimethoprim)?
You should not use this medication if you are allergic to sulfamethoxazole or trimethoprim, if you are pregnant or breast-feeding, or if you have anemia (lack of red blood cells) caused by folic acid deficiency.
Before using sulfamethoxazole and trimethoprim, tell your doctor if you have kidney or liver disease, a folic acid deficiency, asthma or severe allergies, AIDS, a glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency), or if you are malnourished.
Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Sulfamethoxazole and trimethoprim will not treat a viral infection such as the common cold or flu.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
Avoid exposure to sunlight, sunlamps, or tanning beds. This medication can make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use sunscreen (SPF 15 or higher) when you are outdoors.
What should I discuss with my healthcare provider before taking Bactrim DS (sulfamethoxazole and trimethoprim)?
You should not use this medication if you are allergic to sulfamethoxazole or trimethoprim, if you are pregnant or breast-feeding, or if you have anemia (lack of red blood cells) caused by folic acid deficiency.
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before using sulfamethoxazole and trimethoprim, tell your doctor if you have:
• kidney or liver disease;
• a folic acid deficiency;
• asthma or severe allergies;
• AIDS;
• a glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency); or
• if you are malnourished.
FDA pregnancy category C. It is not known whether this is harmful to an unborn baby. Before taking sulfamethoxazole and trimethoprim, tell your doctor if you are pregnant or plan to become pregnant during treatment. Sulfamethoxazole and trimethoprim can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 2 months old. Older adults may be more likely to have side effects while taking this medication.
Showing posts with label drug. Show all posts
Showing posts with label drug. Show all posts
Tuesday, September 21, 2010
AMOXICILLIN
Amoxil
Generic Name: amoxicillin (am OKS i sil in)
Brand Names: Moxacil, Moxin,Emoxyl,Tycil
What is the most important information I should know about Amoxicillin?
Do not use this medication if you are allergic to Amoxicillin or to any other penicillin antibiotic, such as ampicillin (Omnipen, Principen), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others.
Before using Amoxicillin tell your doctor if you are allergic to cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others. Also tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or any type of allergy.
Amoxicillin can make birth control pills less effective, which may result in pregnancy. Before taking Amoxicillin, tell your doctor if you use birth control pills.
Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Amoxicillin will not treat a viral infection such as the common cold or flu. Do not give this medication to another person, even if they have the same symptoms you do.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
What is Amoxicillin?
Amoxicillin is an antibiotic in the penicillin group of drugs. It fights bacteria in your body.
Amoxicillin is used to treat many different types of infections caused by bacteria, such as ear infections, bladder infections, pneumonia, gonorrhea, and E. coli or salmonella infection. Amoxicillin is also sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection. This combination is sometimes used with a stomach acid reducer called lansoprazole (Prevacid).
Amoxicillin may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking Amoxicillin?
Do not use Amoxicillin if you are allergic to amoxicillin or to any other penicillin antibiotic, such as:
• ampicillin (Omnipen, Principen);
• dicloxacillin (Dycill, Dynapen);
• oxacillin (Bactocill); or
• penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids, and others).
Before using Amoxicillin, tell your doctor if you are allergic to any drugs (especially cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others), or if you have:
• asthma;
• liver disease;
• kidney disease;
• a bleeding or blood clotting disorder;
• mononucleosis (also called "mono");
• a history of diarrhea caused by taking antibiotics; or
• a history of any type of allergy.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take Amoxicillin.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Amoxicillin can make birth control pills less effective, which may result in pregnancy. Before taking Amoxicillin tell your doctor if you use birth control pills. Amoxicillin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Generic Name: amoxicillin (am OKS i sil in)
Brand Names: Moxacil, Moxin,Emoxyl,Tycil
What is the most important information I should know about Amoxicillin?
Do not use this medication if you are allergic to Amoxicillin or to any other penicillin antibiotic, such as ampicillin (Omnipen, Principen), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others.
Before using Amoxicillin tell your doctor if you are allergic to cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others. Also tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or any type of allergy.
Amoxicillin can make birth control pills less effective, which may result in pregnancy. Before taking Amoxicillin, tell your doctor if you use birth control pills.
Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Amoxicillin will not treat a viral infection such as the common cold or flu. Do not give this medication to another person, even if they have the same symptoms you do.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
What is Amoxicillin?
Amoxicillin is an antibiotic in the penicillin group of drugs. It fights bacteria in your body.
Amoxicillin is used to treat many different types of infections caused by bacteria, such as ear infections, bladder infections, pneumonia, gonorrhea, and E. coli or salmonella infection. Amoxicillin is also sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection. This combination is sometimes used with a stomach acid reducer called lansoprazole (Prevacid).
Amoxicillin may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking Amoxicillin?
Do not use Amoxicillin if you are allergic to amoxicillin or to any other penicillin antibiotic, such as:
• ampicillin (Omnipen, Principen);
• dicloxacillin (Dycill, Dynapen);
• oxacillin (Bactocill); or
• penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids, and others).
Before using Amoxicillin, tell your doctor if you are allergic to any drugs (especially cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others), or if you have:
• asthma;
• liver disease;
• kidney disease;
• a bleeding or blood clotting disorder;
• mononucleosis (also called "mono");
• a history of diarrhea caused by taking antibiotics; or
• a history of any type of allergy.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take Amoxicillin.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Amoxicillin can make birth control pills less effective, which may result in pregnancy. Before taking Amoxicillin tell your doctor if you use birth control pills. Amoxicillin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Tuesday, August 17, 2010
RANITIDINE
Generic Name: ranitidine (ra NI ti deen)
Brand Names: Ranitid, Neotack, Xantid
Suffering Acid Reflux
naturalhealthandbeautyinfo.com/acidIts Painful, It Burns, But Suffer No More. Try These Proven Remedies
What is ranitidine?
Ranitidine is in a group of drugs called histamine-2 blockers. Ranitidine works by reducing the amount of acid your stomach produces.
Ranitidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Ranitidine also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.
Important information about ranitidine
Before using this medication, tell your doctor if you are allergic to any drugs, or if you have kidney disease, liver disease, or porphyria.
Using ranitidine may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucus. Talk with your doctor about your specific risk of developing pneumonia.
Ranitidine granules and effervescent tablets must be dissolved in water before you take them.
Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.
Avoid drinking alcohol. It can increase the risk of damage to your stomach. It may take up to 8 weeks of using ranitidine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.
Heartburn can be confused with early symptoms of heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, dizziness, pain spreading to the arm or shoulder, sweating, nausea or vomiting, and a general ill feeling.
Before using ranitidine
Do not use this medication if you are allergic to ranitidine.
Ask a doctor or pharmacist if it is safe for you to take ranitidine if you have:
* kidney disease;
* liver disease; or
* porphyria.
The ranitidine effervescent tablet may contain phenylalanine. Talk to your doctor before using this form of ranitidine if you have phenylketonuria (PKU).
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Ranitidine passes into breast milk. Do not take ranitidine without telling your doctor if you are breast-feeding a baby.
See also: Pregnancy and breastfeeding warnings in more details
Using ranitidine may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucus. Talk with your doctor about your specific risk of developing pneumonia.
How should I take ranitidine?
Take ranitidine exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.
Do not crush, chew, or break the ranitidine effervescent tablet, and do not allow it to dissolve on your tongue. The 25-milligram effervescent tablet must be dissolved in at least 1 teaspoon of water before swallowing. The150-milligram effervescent tablet should be dissolved in 6 to 8 ounces of water.
Allow the tablet to dissolve completely in the water, and then drink the entire mixture. If you are giving this medicine to a child, you may draw the liquid mixture into a medicine dropper and empty the dropper into the child's mouth.
Ranitidine granules should be mixed with 6 to 8 ounces of water before drinking.
Measure the liquid form of ranitidine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
It may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.
This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using ranitidine.
Store ranitidine at room temperature away from moisture, heat, and light.
See also: Ranitidine dosage in more detail
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include lack of coordination, feeling light-headed, or fainting.
What should I avoid while taking ranitidine?
Avoid drinking alcohol. It can increase the risk of damage to your stomach.
Ranitidine side effects
Stop using ranitidine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
* chest pain, fever, feeling short of breath, coughing up green or yellow mucus;
* easy bruising or bleeding, unusual weakness;
* fast or slow heart rate;
* problems with your vision;
* fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
* nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice
(yellowing of the skin or eyes).
Less serious ranitidine side effects may include:
* headache (may be severe);
* drowsiness, dizziness;
* sleep problems (insomnia);
* decreased sex drive, impotence, or difficulty having an orgasm; or
* swollen or tender breasts (in men);
* nausea, vomiting, stomach pain; or
* diarrhea or constipation.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect ranitidine?
Before taking ranitidine, tell your doctor if you are taking triazolam (Halcion). You may not be able to use ranitidine, or you may need dosage adjustments or special tests during treatment.
There may be other drugs that can interact with ranitidine, or be affected by ranitidine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
* Your pharmacist can provide more information about ranitidine.
* Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
* Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Brand Names: Ranitid, Neotack, Xantid
Suffering Acid Reflux
naturalhealthandbeautyinfo.com/acidIts Painful, It Burns, But Suffer No More. Try These Proven Remedies
What is ranitidine?
Ranitidine is in a group of drugs called histamine-2 blockers. Ranitidine works by reducing the amount of acid your stomach produces.
Ranitidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Ranitidine also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.
Important information about ranitidine
Before using this medication, tell your doctor if you are allergic to any drugs, or if you have kidney disease, liver disease, or porphyria.
Using ranitidine may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucus. Talk with your doctor about your specific risk of developing pneumonia.
Ranitidine granules and effervescent tablets must be dissolved in water before you take them.
Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.
Avoid drinking alcohol. It can increase the risk of damage to your stomach. It may take up to 8 weeks of using ranitidine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.
Heartburn can be confused with early symptoms of heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, dizziness, pain spreading to the arm or shoulder, sweating, nausea or vomiting, and a general ill feeling.
Before using ranitidine
Do not use this medication if you are allergic to ranitidine.
Ask a doctor or pharmacist if it is safe for you to take ranitidine if you have:
* kidney disease;
* liver disease; or
* porphyria.
The ranitidine effervescent tablet may contain phenylalanine. Talk to your doctor before using this form of ranitidine if you have phenylketonuria (PKU).
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Ranitidine passes into breast milk. Do not take ranitidine without telling your doctor if you are breast-feeding a baby.
See also: Pregnancy and breastfeeding warnings in more details
Using ranitidine may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucus. Talk with your doctor about your specific risk of developing pneumonia.
How should I take ranitidine?
Take ranitidine exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.
Do not crush, chew, or break the ranitidine effervescent tablet, and do not allow it to dissolve on your tongue. The 25-milligram effervescent tablet must be dissolved in at least 1 teaspoon of water before swallowing. The150-milligram effervescent tablet should be dissolved in 6 to 8 ounces of water.
Allow the tablet to dissolve completely in the water, and then drink the entire mixture. If you are giving this medicine to a child, you may draw the liquid mixture into a medicine dropper and empty the dropper into the child's mouth.
Ranitidine granules should be mixed with 6 to 8 ounces of water before drinking.
Measure the liquid form of ranitidine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
It may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.
This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using ranitidine.
Store ranitidine at room temperature away from moisture, heat, and light.
See also: Ranitidine dosage in more detail
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include lack of coordination, feeling light-headed, or fainting.
What should I avoid while taking ranitidine?
Avoid drinking alcohol. It can increase the risk of damage to your stomach.
Ranitidine side effects
Stop using ranitidine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
* chest pain, fever, feeling short of breath, coughing up green or yellow mucus;
* easy bruising or bleeding, unusual weakness;
* fast or slow heart rate;
* problems with your vision;
* fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
* nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice
(yellowing of the skin or eyes).
Less serious ranitidine side effects may include:
* headache (may be severe);
* drowsiness, dizziness;
* sleep problems (insomnia);
* decreased sex drive, impotence, or difficulty having an orgasm; or
* swollen or tender breasts (in men);
* nausea, vomiting, stomach pain; or
* diarrhea or constipation.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect ranitidine?
Before taking ranitidine, tell your doctor if you are taking triazolam (Halcion). You may not be able to use ranitidine, or you may need dosage adjustments or special tests during treatment.
There may be other drugs that can interact with ranitidine, or be affected by ranitidine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
* Your pharmacist can provide more information about ranitidine.
* Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
* Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Friday, August 6, 2010
Paracetamol
Paracetamol is a common medicine to everybody. It is most useful and well known to everybody. All of doctors prescribe this medicine often. There is no man who does not use paracetamol. Somebody uses this medicine without suggestion of doctor. But it is very risky to use any kind of medicine without prescription of a doctor.
PARACETAMOL
Paracetamol is a common medicine to everybody. It is most useful and well known to everybody. All of doctors prescribe this medicine often. There is no man who does not use paracetamol. Somebody uses this medicine without suggestion of doctor. But it is very risky to use any kind of medicine without prescription of a doctor.
PHARMACOLGY
Paracetamol is the formulation of Paracetamol, which is one of the safest and most widely used analgesic and antipyretic. Paracetamol produce analgesic action by elevation of the pain threshold and antipyretic through action on the hypothalamic heat regulation centre. Paracetamol exerts significantly milder side effects and most unlikely to produce many of the serious side effects associated with aspirin and other NSAIDs. Paracetamol is rapidly and completely absorbed from the G.I.T. following oral administration and from rectum after rectal administration. The mean half-life of absorption from the upper small intestine is only 7 minutes. The drug is extensively metabolized in the liver and it has a plasma half- life 1.5 to 3.0 hours. Paracetamol is not bound to plasma proteins to any extent.
INDICATION
Fever, Common cold and influenza, Headache, Toothache, Earache, Body ache, Myalgia, Dysmenorrheal, Neuralgia and Sprains. Pain of colic, back pain, post-operative pain, chronic pain of cancer, inflammatory pain and post vaccination pain and fever of children. Rheumatism and osteoarthritis pain & stiffness of joints in fingers, hips, knees, wrist, elbows, feet, ankles and top & bottom of the spine.
DOSAGE AND ADMINISTRATION
Adult : 1-2 tablets every 4 to 6 hours up to a maximum of (8 tablets) daily.
Children : (6-12) years ½ to 1 tablets 3 to 4 times daily. For long term
treatment, It is wise not to exceed the dose beyond 2.6gm/day.
SYRUP and SUSPENSION
Children Under 3 months : 10mg/kg body weight (reduce to 5 mg/kg if jaundiced)
3 to 4 times daily
3 months to below 1 year: ½ teaspoonful 3 to 4 times daily.
6-12 years : 2-4 teaspoonfuls 3 to 4 times daily.
Adults :4-8 teaspoonfuls 3 to 4 times daily.
CONTRAINDICATION
Known sensitivity to paracetamol.
SIDE EFFECTS
Side effects are significantly mild, though hematological reactions have been reported. Pancreatitis, Skin rashes and other allergic reactions occur occasionally
OVER DOSE
Moderate overdose : 4-10gm/day
Excessive overdose : More than 10mg/day.
Symptoms of overdose include pallor, nausea, vomiting, anorexia & abdominal pain. Liver damage may become apparent 12-48 hours after ingestion.
In severe poisoning hepatic failure may progress to encephalopathy, coma & DEATH.
example- Ace, Napa, Reset, Renova, Xcel
PARACETAMOL
Paracetamol is a common medicine to everybody. It is most useful and well known to everybody. All of doctors prescribe this medicine often. There is no man who does not use paracetamol. Somebody uses this medicine without suggestion of doctor. But it is very risky to use any kind of medicine without prescription of a doctor.
PHARMACOLGY
Paracetamol is the formulation of Paracetamol, which is one of the safest and most widely used analgesic and antipyretic. Paracetamol produce analgesic action by elevation of the pain threshold and antipyretic through action on the hypothalamic heat regulation centre. Paracetamol exerts significantly milder side effects and most unlikely to produce many of the serious side effects associated with aspirin and other NSAIDs. Paracetamol is rapidly and completely absorbed from the G.I.T. following oral administration and from rectum after rectal administration. The mean half-life of absorption from the upper small intestine is only 7 minutes. The drug is extensively metabolized in the liver and it has a plasma half- life 1.5 to 3.0 hours. Paracetamol is not bound to plasma proteins to any extent.
INDICATION
Fever, Common cold and influenza, Headache, Toothache, Earache, Body ache, Myalgia, Dysmenorrheal, Neuralgia and Sprains. Pain of colic, back pain, post-operative pain, chronic pain of cancer, inflammatory pain and post vaccination pain and fever of children. Rheumatism and osteoarthritis pain & stiffness of joints in fingers, hips, knees, wrist, elbows, feet, ankles and top & bottom of the spine.
DOSAGE AND ADMINISTRATION
Adult : 1-2 tablets every 4 to 6 hours up to a maximum of (8 tablets) daily.
Children : (6-12) years ½ to 1 tablets 3 to 4 times daily. For long term
treatment, It is wise not to exceed the dose beyond 2.6gm/day.
SYRUP and SUSPENSION
Children Under 3 months : 10mg/kg body weight (reduce to 5 mg/kg if jaundiced)
3 to 4 times daily
3 months to below 1 year: ½ teaspoonful 3 to 4 times daily.
6-12 years : 2-4 teaspoonfuls 3 to 4 times daily.
Adults :4-8 teaspoonfuls 3 to 4 times daily.
CONTRAINDICATION
Known sensitivity to paracetamol.
SIDE EFFECTS
Side effects are significantly mild, though hematological reactions have been reported. Pancreatitis, Skin rashes and other allergic reactions occur occasionally
OVER DOSE
Moderate overdose : 4-10gm/day
Excessive overdose : More than 10mg/day.
Symptoms of overdose include pallor, nausea, vomiting, anorexia & abdominal pain. Liver damage may become apparent 12-48 hours after ingestion.
In severe poisoning hepatic failure may progress to encephalopathy, coma & DEATH.
example- Ace, Napa, Reset, Renova, Xcel
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